Feb 3, 2026 · Infectious mononucleosis, primarily caused by Epstein-Barr virus (EBV), leads to splenomegaly in ~50 - 60% of cases due to immunoblastic infiltration and red pulp expansion.

Peripheral blood film in infectious mononucleosis by Epstein-Barr virus. Infectious mononucleosis (IM) is associated with primary infection by Epstein–Barr virus (EBV), a gamma herpesvirus.

Infectious mononucleosis caused by Epstein-Barr Virus (EBV) produces tonsillar enlargement and lymphadenopathy in children and young adults. Initially, there is follicular hyperplasia with …

The histopathology of infectious mononucleosis was described in 1920 by Sprunt and Evans, whose findings were based on lymph node biopsy sections from three of six individuals who were afflicted …

May 25, 2012 · In this study, we describe the morphological and immunophenotypic features that are shared by these cases of infectious mononucleosis mimicking lymphoma and may be helpful in their …

The main histopathologic features of infectious mononucleosis are described. In the lymph nodes, the principal change is the appearance of numerous large pyroninophilic cells (immunoblasts), initially …

May 22, 2024 · EBV latency within B cells usually starts with type III in primary infection, to latency II while selecting pressure locally and type I that allows virus survival without expression of other viral …

Aug 1, 2012 · In this study, we describe the morphological and immunophenotypic features that are shared by these cases of infectious mononucleosis mimicking lymphoma and may be helpful in their …

May 9, 2024 · What is it Infectious mononucleosis is a contagious disease most commonly caused by Epstein-Barr virus (EBV). Other viruses can also cause this disease. Infectious mononucleosis is …

Infectious mononucleosis was the name coined by Sprunt and Evans (Sprunt 1920) to describe a syndrome that resembled an acute infectious disease accompanied by atypical large peripheral …